Research & Publications
Advancing the field of congenital heart disease through innovative research and scholarship
56+
Publications & Presentations
$124K
Research Funding
3
Research Grants
Research Focus Areas
Dr. Charla's research program focuses on improving outcomes and quality of life for patients with congenital heart disease through innovative clinical investigations and translational research.
Primary Research Areas
- Fontan physiology and novel therapeutic interventions
- Heart failure management in congenital heart disease
- Advanced cardiac imaging and hemodynamic assessment
- Pregnancy outcomes in women with heart disease
Methodologies
- Cardiac MRI with flow quantification
- Clinical outcomes research
- Systematic reviews and meta-analyses
- Program development and quality improvement
Research Grants & Funding
Feasibility and Efficacy of Biphasic Cuirass Ventilation in the Ambulatory Fontan population: Cardiovascular flow assessments by MRI
$24,840
Health Innovations Clinical Research Grant•Principal Investigator•2019–2020
Efficacy and Feasibility of Negative Pressure Ventilation in Fontan patients
$75,000
Peter Munk Cardiac Center Innovation Fund•Co-Principal Investigator•2016–2018
Efficacy and Feasibility of negative pressure ventilation in Fontan patients
$24,350
SickKids Labatt Heart Center Innovation Fund•Co-Principal Investigator•2016–2018
$124,190
Total Research Funding Awarded
Publications & Presentations
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Augmentation of the Pulmonary Blood Flow and Cardiac Output by Non-Invasive External Ventilation Late After Fontan Palliation
Charla P, Karur G, Yamamura K, Yoo SH, Granton J, Oechslin E, Shah A, Benson L, Mertens L, Alonso-Gonzalez R, Hanneman K, Wald R
Heart Journal•2020Fontan Physiology
Pulmonary arterial hypertension in pregnancy: a systematic review of outcomes in the modern era
Low TT, Guron N, Ducas R, Yamamura K, Charla P, Granton J, Silversides CK
Pulmonary Circulation•2021Cardio-Obstetrics
Lateral Tunnel Fontan Atrial Ablation Trans-Baffle Access Is Not Mandatory as the Initial Strategy
Bhaskaran A, Nayyar S, Charla P, Saeed Y, Haldar S, Porta-Sanchez A, Kugamoorthy P, Jons C, Oechslin E, Hickey E, Harris L, Silversides C, Roche L, Downar E, Nanthakumar K, Nair K
Journal of Interventional Cardiac Electrophysiology•2019ACHD
Transmural circumflex infarction in a young Fontan patient: to leave home to find it
Meier LM, Van De Bruaene A, Charla P, Wald RM, Oechslin E
European Heart Journal•2018ACHD
Reliability of The Cardiac Output Measurements During Catheterization: Comparison of Various Commonly Used Formulae Calculating Assumed O2 Consumption
Kendall G, Kirkwood G, Schneider H, Mahadevan V, Stokes A, Karadakhy O, Carmichael J, Nagra R, Yearoo T, Patel M, Hama B, Gill A, Shauq A, Hoschtitzky A, Jenkins P, Dua J, Shah P, Charla P, Shah A
JACC Interventions•2018ACHD
Creating a Fontan Fenestration in a Child with Dextrocardia and Interrupted Inferior Vena Cava
Charlagorla P, Breinholt J
Annals of Pediatric Cardiology•2016Pediatric Cardiology
Congenital pulmonary vein stenosis: Encouraging midterm outcomes
Charlagorla P, Becerra D, Patel P, Turrentine M, Hoyer MH, Darragh R
Journal of Pediatric Cardiology•2015Pediatric Cardiology
Metabolic scaling and twin pregnancies
Salafia CM, Kiryankova N, Inany H, Charlagorla P, Park M, Kwahar N, VanHorn S, Dygulska B, Narula P, Lederman S
Journal of Placenta•2015Pediatric Cardiology
Fetal intestinal perforation and meconium peritonitis associated with maternal autoimmune hepatitis
Charlagorla P, Sublett S, Kessler E, Gad A
Journal of Neonatal-Perinatal Medicine•2014Pediatric Cardiology
Loss of plasma membrane integrity, complement response and formation of reactive oxygen species during early myocardial ischemia/reperfusion
Charlagorla P, Liu J, Patel M, Rushbrook JI, Zhang M
Molecular Immunology•2013Cardiac Imaging
Histologic chorioamnionitis as a consideration in the management of newborns of febrile mothers
Hoang D, Charlagorla P, Salafia C, VanHorn S, Dygulska B, Narula P, Gad A
Journal of Maternal-Fetal Neonatal Medicine•2013Pediatric Cardiology
The superiority of targeted neonatal echocardiography for umbilical venous catheter tip localization: accuracy of a clinician performance model
Pulickal AS, Charlagorla PK, Tume SC, Chhabra M, Narula P, Nadroo AM
Journal of Perinatology•2013Pediatric Cardiology
Vessel enhancement with multiscale and curvilinear filter matching for placenta images
Mark P, Yampolsky M, Shlakhter O, VanHorn S, Dygulska B, Kiryankova N, Inany H, Charlagorla PK, Salafia C
Placenta•2013Cardiac Imaging
Assessment of Cardiac Parameters in Large for Gestational Age Infants in Mothers with & without Gestational Diabetes: Correlation with Placental Pathology
Charlagorla P, Inany H, Gudavalli M, Chhabra M, Salafia C, Dygulska B, Narula P, Gad A
Placenta•2013Cardio-Obstetrics
Research Collaboration Opportunities
Interested in collaborating on congenital heart disease research? Dr. Charla welcomes opportunities for academic partnerships and joint investigations